Container Closure Integrity Testing of Intravenous Bags
IV bags can be effectively tested using VeriPac Vacuum Decay technology. PTI’s VeriPac Vacuum Decay technology is capable of detecting package leaks and invisible defects using a differential pressure transducer leak test system. The method is deterministic, non-subjective and requires no sample preparation. The VeriPac leak detection system is connected to a test chamber containing the IV bag. The test is conducted by drawing vacuum on the IV bag in the test chamber and monitoring for any changes in vacuum level. In case of a defective package, air or fluid will leak from the package into the chamber causing a change in pressure. Non-leaking packages do not leak any pressure into the chamber holding the chamber vacuum level constant.
The VeriPac system provides quantitative test result data to ensure leak detection and reduce false positives. Regardless of defect location, the vacuum decay system can detect both large and small defects. Case studies have proven that each defect type was tested multiple times to determine defect detection capability. The cycle time for the IV bag testing is fast, sensitive and repeatable for both liquid and gas leaks.
A range of IV bag test chamber configurations depending on IV bag dimensions, profile (thin vs. thick) and fill volume are available. Test sensitivity will depend on fill volume and package size. Both standard and customized solutions are available to achieve the optimal inspection solution for each IV bag application.
VeriPac Technology Benefits:
- VeriPac solutions leak test the entire IV bag including weld and port regions that are subject to damage and stress
- Test chambers are designed to accommodate various IV bag profiles, fill volume and thickness
- Reliable, consistent and repeatable leak detection