Vacuum Decay

Vacuum decay is a container integrity test method taking advantage of the fundamental physical properties. This test method which was proved over decades has been improved with the advancement of technology.

Vacuum decay has been substantiated as one of the most practical and sensitive vacuum-based leak detection method. This test gives a reliable, reproducible, repeatable and accurate quantitative result with a pass or fail determination.

Packages can be non-destructively evaluated using the VeriPac inspection method which is based on vacuum decay technology. Package types include filled and sealed rigid, semi-rigid and flexible packaging made of non-porous or porous materials. This vacuum decay method developed by PTI’s VeriPac instruments are capable of detecting leaks in the single digit micron range.

VeriPac Vacuum Decay Technology

VeriPac leak testers connect to a test chamber that is specially designed to contain the package to be tested. The package is placed inside the test chamber to which vacuum is applied. The single or dual vacuum transducer technology is used to monitor the test chamber for both the level of vacuum as well as the change in vacuum over a predetermined test time. The changes in absolute and differential vacuum indicate the presence of leaks and defects within the package. The sensitivity of a test is a function of the package design, the package test fixture and critical test parameters of time and pressure. Test systems can be designed for manual or fully automated operation. This inspection method is suitable for laboratory offline testing and production applications for QA/QC statistical process control. The test cycle takes only a few seconds, is non-invasive and non-destructive to both product and package.

VeriPac inspection systems utilize an ASTM approved vacuum decay leak test method (F2338) recognized by the FDA as a consensus standard for package integrity testing. This test method was developed using VeriPac leak test instruments. Vacuum decay technology is also referenced in the new USP <1207> Chapter Guidance as a deterministic test method for package integrity testing. This method is also listed in ISO 11607.

The criteria for selecting the appropriate VeriPac model is based on the type of package and leak test sensitivity desired. Configurations can be optimized with either single or dual high-resolution transducers as well as type of vacuum supply, i.e. internal, external, high vacuum, etc.

PTI advances in high vacuum testing and developed the next generation PERMA- VAC technology that addresses vacuum decay detection at the very core of physical test measurement, controlling the test system volume and maximizing the SNR between good and defective samples. The PERMA-VAC technology advancements make the VeriPac line of test systems the most sensitive and reliable vacuum-based leak test available on the market.

Show more Show Less

VeriPac Vacuum & Pressure Decay Technology

The VeriPac Delta is a next generation package integrity leak detection system featuring the flexibility to accommodate a wide range of products and packaging formats. With the capability to detect leak rates as low as 5 micron depending on package specifications, the VeriPac Delta is the optimal non-destructive quantitative test method for many pharmaceutical and food applications.

This system is specifically designed to test containers for gas leaks for dry products (lyophilized vials, powder filled) as well as test for liquid leaks (liquid filled vials prefilled syringes). The VeriPac Delta features two core technologies, Vacuum decay and Pressure decay. Vacuum decay technology is based on the ASTM vacuum decay leak test method (F2338-09) recognized by the FDA as a consensus standard for package integrity testing. This test method was developed using VeriPac leak test instruments. Vacuum decay detection is down to 5 microns. Pressure decay detection is down to 10 microns, with a rapid test time of only 10 seconds. Two highly sensitive leak testing technologies in one convenient benchtop laboratory system provide a versatile container closure integrity solution for many pharmaceutical applications.

VeriPac Delta Technology

The VeriPac Delta leak tester connects to a test chamber that is specially designed to contain the package to be tested either rigid containers or flexible packaging. The package is placed inside the test chamber to which vacuum or pressure is applied. The high resolution absolute transducer technology is used to monitor the test chamber for both the level of vacuum or pressure as well as the change in vacuum or pressure over a predetermined test time and is capable of detecting gross and micro leaks. The test cycle takes only a few seconds, results are non-subjective and testing is nondestructive to both product and package. The sensitivity of a test is a function of the sensitivity of the transducer, the package design, the package test fixture and critical test parameters of time and pressure. Test systems can be designed for manual or semi-automatic operation. This inspection method is suitable for laboratory offline testing and QA/QC statistical process control.

Show more Show Less

914.337.2005

Vacuum Decay

Vacuum Decay

Download

VeriPac Vacuum Decay Technology

VeriPac Vacuum & Pressure Decay Technology

VeriPac Delta Technology